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Newest Principles of Development summaries
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Complete summary of all lectures of the molecular principles of development course
- Summary • 43 pages • 2020
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All lectures summarized into detail including experimental evidence given during the lectures.
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Lectures molecular principles of development
- Summary • 51 pages • 2020
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All lectures of the course molecular principles of development (NWI-BB084B) are covered in the document (using powerpoint slides, additional information from the lectures and the book). The book used for this course was: molecular principles of development, the 6th Revised edition. The pictures included are taken from the PowerPoint slides and the book. I passed the course using this document.
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Summary lectures Molecular Principles Of Development (NWI-BB084B)
- Summary • 58 pages • 2021
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This is a summary of all lectures in the course.
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Molecular Principles of Development: Summary of lectures and self-study assignments, NWI-BB084B
- Summary • 59 pages • 2020
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An extensive summary of the information given during the course Molecular Principles of Development (NWI-BB084B) in English. With images, self-study assignments and developmental processes incorporated and explained.
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13. Histone Modifications
- Class notes • 9 pages • 2020
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- Provide an overview of the polycomb and trithorax group complexes and their activities
- Describe evidence that indicates stem cell chromatin is in an open ‘permissive’ state
- Understand what is bivalent chromatin and why it may be important for stem cell biology and development
- Understand the steps of chromatin immunoprecipitation and why it is a useful technique in epigenetic studies
- Describe the Nodal signalling example and experimental approach, and understand how it illustrates ...
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15. Genomic Imprinting
- Class notes • 8 pages • 2020
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- To give an overview of genomic imprinting, when it is initiated and how imprinting disorders can arise
- Describe key events in X-inactivation including the role of the Xist non-coding RNA
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11. Small Changes Big Differences
- Class notes • 10 pages • 2020
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- Understand how the neural crest contributes to cardiac development and the pathology underlying congenital cardiac abnormalities.
- Explain how certain SNPs might contribute to congenital abnormalities.
- Discuss the evidence that Notch signalling is important during cardiac morphogenesis
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6. Limb Development
- Class notes • 7 pages • 2020
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- Identify the important signalling centres in the developing limb bud and describe the experiments that identified these centres and demonstrated their importance.
- Describe the experimental evidence for the role of FGF signalling in limb bud outgrowth
- Describe the experimental evidence that shows that Shh acts as a morphogen to pattern the anterior-posterior axis of the limb bud.
- Describe how the important signalling centres in the limb bud co-ordinately regulate pattern formation in the ...
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12. Epigenetics Introduction
- Class notes • 10 pages • 2020
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- To have gained an understanding of why epigenetics is relevant to development
- To understand that DNA methylation can impact gene expression and be able to describe an experimental approach to test this
- To explain how patterns of DNA methylation can be maintained through DNA replication
- To understand that covalent histone modifications form a code that can impact gene expression
- To explain how some histone modifications can be maintained through DNA replication
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9. Backs & Fronts
- Class notes • 7 pages • 2020
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- Discuss the evidence supporting a role for tinman homologues in heart development
- Discuss the anatomical and molecular evidence supporting the theory of dorsoventral axis inversion during the evolution of protostome and deuterostome lineages.
- Describe the conserved features of Hox gene cluster organisation.
- Appreciate and discuss how changes in the expression and activity of Hox genes have contributed to changes in anatomy during animal evolution.
- Draw conclusions regarding the molecul...