Presystemic metabolism Study guides, Class notes & Summaries

NU578 - Unit 1 Test With Correct Answers...

what is bioavailability? - Correct Answer-The fraction of the drug that reaches systemic circulation what does bioavailability depend on? - Correct Answer-Depends on solubility, chemical structure, size (large molecules have harder time), polarity/charge, presystemic biotransformation (how it is metabolized) Biotransformation (metabolism) and elimination of drugs contribute do bioavailability. - Correct Answer-True First order kinetics: - Correct Answer-means that a constant fraction of...

Chapter 1 The Foundation of Pharmacology: Quality and Safety 1. A woman has been prescribed paroxetine hydrochloride, which is an antidepressant agent administered in pill form. The medication is administered for her obsessivecompulsive disorder. This medication will produce which of the following effects? A) Curative B) Systemic C) Local D) Parenteral Ans: B Feedback: Drugs that produce systemic effects are taken into the body, circulated through the bloodstream to their sites o...

Question: Signs and symptoms of digitalis toxicity include: constipation and muscle spasms. bradycardia and tinnitus. headache and dizziness. blurred vision and persistent diarrhea. Correct Explanation: Signs and symptoms of digitalis toxicity include: confusion, irregular pulse, loss of appetite, nausea, vomiting, diarrhea, fast heart beat, and visual changes (blurred vision, blind spots, green-yellow color disturbances, halo effect). Regardless of route of administrat...

NSG 6320 AGNP BOARD EXAM QUESTIONS CARDIOVASCULAR PRESCRIBING Question: Signs and symptoms of digitalis toxicity include: constipation and muscle spasms. bradycardia and tinnitus. headache and dizziness. blurred vision and persistent diarrhea. Correct Explanation: Signs and symptoms of digitalis toxicity include: confusion, irregular pulse, loss of appetite, nausea, vomiting, diarrhea, fast heart beat, and visual changes (blurred vision, blind spots, green-yellow color...