MMG 141

Trinucleotide Repeat Expansion correct answer: Mutation that results in expansion of the number of trinucleotide repeats Trinucleotide Repeat (TNR) correct answer: Sequence of three nucleotides repeated several times in tandem Chromosomal Alteration correct answer: Mutation that involves >100 bp Spontaneous Mutation correct answer: A mutation that arises in the absence of a mutagenic agent. Unavoidable, happens in the natural process Hydrolysis correct answer: The process of...

Aneuploidy correct answer: A chromosome that is not an exact multiple of a haploid set Monosomy (2n-1) correct answer: One less chromosome than the diploid number Trisomy (2n+1) correct answer: One more chromosome than the diploid number Nondisjunction correct answer: The most common cause of aneuploidy Nondisjunction correct answer: Error in meiosis during gamete formation Autosomal Monosomy correct answer: Universally lethal Autosomal Trisomy correct answer: Most are l...