NAPLEX

Renal Disease correct answer: Common Causes -*DM* -*HTN* AKI -*sudden* loss of kidney function -commonly caused by *dehyration* -*BUN:SCr ration > 20:1* CKD -*progressive* loss of kidney function -*GFR or CrCl* < 60 -*albuminurua * > 30 or more albumin spilling into urine -*treat* with ACE or ARB (*if Scr increased up to 30% do not stop tx*) ESRD -*permanent kidney function* Renal Physiology -*to control sodium and water* to regulate *blood volume* and *blood ...

Common CYP Inhibitors correct answer: G: Grapefruit Pacman: Protease Inhibitors (ritonavir) Azole antifungals: Fluconazole, ketoconazole, ect. Cyclosporine Macrolides: Clarithromycin, erythromycin, not azith Amiodarone Non-DHP CCBs: Dilt and verap CYP Inducers correct answer: Phenytoin Smoking Phenobarbital Oxacarbazepine Rifampin Carbamazepine St. John's wort P-gp Substrate correct answer: Antiocoags: apixaban, edoxaban CVD Drugs: digoxin, dilt, carvedilol Immunosuppr...

How do you convert Aminophylline to Theophylline dosing? correct answer: Aminophylline dose x 0.8= Theophylline dose How do you convert Theophylline to Aminophylline dosing? correct answer: Theophylline dose / 0.8 = Aminophylline dose How many grains are in 81 mg aspirin? correct answer: 1 1/4 1 grain = ___ mg correct answer: 65 What waist circumference (inches) for women and men is considered high risk for co-morbidities? correct answer: >35 (inches) women, >40 (inches) m...

Drugs to decrease when using amiodarone (ami will ^ conc) correct answer: digoxin, warfarin, quinidine, procainamide 1A2 inducers correct answer: PS PORES, E is for estrogen. (Phenytoin, Smoking, Phenobarbital, Oxcarbazepine, Rifampin (rifabutin, rifapentin), Carbamazepine, St. John's Wort) CYP 450 Inducers correct answer: PS PORCS (Phenytoin, Smoking, Phenobarbital, Oxcarbazepine, Rifampin (rifabutin, rifapentin), Carbamazepine, St. John's Wort) CYP 450 Inhibitors correct answer: ...

Which of the following statements concerning use of Precedex in critical care patients is correct? A It can only be used if the patient is intubated. B It can only be used if the patient is also receiving a paralytic. C It will decrease blood pressure. D It is indicated for use up to 72 hours. E It is more likely to cause delirium than a benzodiazepine. correct answer: It will decrease blood pressure. MH is a 65 year old post-menopausal female with a family history of breas...

CMEA requires purchasers of scheduled listed chemical products to present a photo ID. Which of the following items is not an acceptable form of identification? correct answer: An employer-based security ID A 76-year-old male with a past medical history of hypertension, myocardial infarction one year ago, and normal left ventricular ejection fraction is receiving lisinopril and chlorthalidone daily. He now presents to the emergency room with a 2-week history of palpitations, dizziness, leg sw...

Dissociation factor (i) for 1 dissociated ion correct answer: 1 Dissociation factor (i) for 2 dissociated ions correct answer: 1.8 Dissociation factor (i) for 3 dissociated ions correct answer: 2.6 Dissociation factor (i) for 4 dissociated ions correct answer: 3.4 Dissociation factor (i) for 5 dissociated ions correct answer: 4.2 What type of data is continuous data? correct answer: Ratio and interval What type of data is discrete or categorical data? correct answer: Nom...

What are the prophylaxis doses of Lovenox (enoxaparin)? correct answer: 30mg SQ q12H or 40mg SQ daily (CrCl < 30ml/min use 30mg SQ daily) (Tx dose is 1mg/kg q12H) What is the treatment dose for Lovenox (enoxaparin)? correct answer: Tx dose is 1mg/kg q12H (Prophylaxis doses 30mg SQ q12H or 40mg SQ daily) What is the dose of Lovenox (enoxaparin) when CrCl < 30ml/min)? correct answer: 30mg SQ daily What is Prandin's class? correct answer: meglitinide What is the MOA of meg...

What is the definition of hypertension? correct answer: BP > 140/90 OR Patient requires antihypertensive therapy Chronic uncontrolled HTN can lead to target organ damage. What organs or organ systems are typically affected? correct answer: 1) Cardiac (MI, need for CABG, PCI, left ventricular hypertrophy, CHF with reduced EF) 2) Cerebrovascular (stroke, TIA) 3) Renal (CKD) 4) Ophthalmologic (retinopathy, blindness) 5) Vascular (peripheral arterial disease) What are blood pressur...

1 cup = ____ mL correct answer: 236.56 mL 1 pint = ___ mL correct answer: 473mL 1 quart = ___ mL correct answer: 946 mL 1 gallon = ___ mL correct answer: 1 gallon = 3785 mL specific gravity = correct answer: g / mL sg x w/w (%) = w/v (%) ou od os ad au as correct answer: ou = both eyes od = right eye os = left eye ad = ear right au = ear both as = ear left BSA calculation correct answer: Mostellar formulation: square root of (cm x kg)/3600 1 grain = ____ ...